Launcher Grenades require a grenade launcher, which is stand alone or underslung. Grenade Launchers are firearms and require that production path.
Missiles and Missle Launchers require a team, building them from scratch is unrealistic.
Note to Players: Information here is considered metagaming. Your character should not reference or use these numbers in game to determine who should roll for specific skills.
Book 2, page 22, "This Skill functions with respect to producing 'simple' explosives such as TNT, nitroglycerine, blasting caps, etc., as Pharmacy Skill does with respect to drugs." Book 2, page 23, "This Skill is an advanced form of Simple Explosives Skill and operates in the smae way but deals with more advanced explosives such as plastic explosives and other such wonders of modern technology."